Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients.

نویسندگان

  • Edward J Howe
  • Babatunde O Okesola
  • David K Smith
چکیده

A simple supramolecular hydrogel based on 1,3:2,4-di(4-acylhydrazide)benzylidene sorbitol (DBS-CONHNH2), is able to extract acid-functionalised anti-inflammatory drugs via directed interactions with the self-assembled gel nanofibres. Two-component hydrogel-drug hybrid materials can be easily formed by mixing and exhibit pH-controlled drug release.

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عنوان ژورنال:
  • Chemical communications

دوره 51 35  شماره 

صفحات  -

تاریخ انتشار 2015